cell 625 words KG: ent-gene-8c4c3123 2026-03-24
kind:cell-typesection:cell-typesstate:published
Contents

BDNF Neurons

🔬 Protein Info
Gene Symbolent-gene-8c4c3123
CategoryNeurotrophin-producing neurons
Core ligandBDNF
Primary receptor axisTrkB, p75NTR
High-relevance systemsHippocampus, cortex, basal forebrain, mesolimbic circuits
Key disease linksAlzheimer's Disease, Parkinson's Disease, Huntington-related corticostriatal dysfunction
KG Connections2 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (12)

Hippocampal CA3-CA1 synaptic rescue via DHHC2-mediated PSD95
Score: 0.69
Multiplexed Base Editing for Simultaneous Neuroprotective Ge
Score: 0.53
Epigenetic Memory Reprogramming for Alzheimer's Disease
Score: 0.47
Neuroplasticity-Enhanced Learning Hypothesis
Score: 0.42
Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.68

Related Analyses (15)

CRISPR-based therapeutic approaches for neurodegenerative di
neurodegeneration · archived
Selective vulnerability of entorhinal cortex layer II neuron
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Digital biomarkers and AI-driven early detection of neurodeg
neurodegeneration · archived
Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived

Related Experiments (19)

Synaptic plasticity and protein expression analysis in mPFC
exploratory · proposed · Score: 0.85
AD Amyloid-Resilient Phenotype Study — Why Some amyloid-Posi
clinical · proposed · Score: 0.40
AD Combination Therapy Trial: Anti-Aβ + Anti-Tau
clinical · proposed · Score: 0.40
Alpha-Synuclein Aggregation Triggers — Sporadic PD Initiatio
clinical · proposed · Score: 0.40
Alpha-Synuclein Spreading Mechanism — Prion-Like Propagation
exploratory · proposed · Score: 0.40

See Also (2)

BDNF - Neurotrophic Factor Biomarker
biomarker · Pages share 4 hypotheses
OSK Reprogramming and Yamanaka Factors in Neurodegenera
mechanism · Pages share 3 hypotheses

Knowledge Graph (2 edges)

ent-gene-8c4c3123 data_in benchmark_ot_ad_answer_key:BDNF
benchmark_ot_ad_answer_key:BDNF data_in ent-gene-8c4c3123