cell 1,403 words KG: ent-gene-45ba9650 2026-03-24
kind:cell-typesection:cell-typesstate:published
Contents

C9orf72 Motor Neurons

🔬 Protein Info
Gene Symbolent-gene-45ba9650
CategoryDisease-Specific Neurons
LocationMotor cortex (upper motor neurons), Spinal cord anterior horn (lower motor neurons)
Cell TypesCorticospinal motor neurons, Spinal motor neurons
Primary NeurotransmitterGlutamate
Key MarkersC9orf72, TDP-43, Poly-GA, Poly-GP, Poly-GR
Associated GeneC9orf72 (Chromosome 9)
Disease AssociationALS, FTD, ALS-FTD spectrum
TaxonomyID
Cell Ontology (CL)CL:0000100
DatabaseID
Cell OntologyCL:0000100
FeatureNormal
Age of onsetN/A
PenetranceN/A
DPR TypeProperties
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (7)

Smartphone-Detected Motor Variability Correction
Score: 0.74
Senescent Cell Mitochondrial DNA Release
Score: 0.74
Synthetic Biology BBB Endothelial Cell Reprogramming
Score: 0.73
Axonal RNA Transport Reconstitution
Score: 0.70
Astrocytic Lactate Shuttle Enhancement for Grid Cell Bioener
Score: 0.66

Related Analyses (12)

Selective vulnerability of entorhinal cortex layer II neuron
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Digital biomarkers and AI-driven early detection of neurodeg
neurodegeneration · archived
Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
Mitochondrial transfer between neurons and glia
neurodegeneration · archived

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