cell 1,753 words KG: ent-gene-8cd44c77 2026-03-27
kind:cell-typesection:cell-typesstate:published
Contents

Hypothalamic Arcuate NPY Neurons

🔬 Protein Info
Gene Symbolent-gene-8cd44c77
Co-release NPY and AgRPPotent orexigenic signals
Respond to energy stateMonitor metabolic status
Project widelyTo other hypothalamic nuclei
LeptinSatiety signal
InsulinMetabolic signal
GlucoseEnergy availability
Dorsal regionAdjacent to the ventromedial hypothalamus
Ventrolateral regionNear the median eminence
Rostrocaudal extentSpans from the preoptic area to the mammillary bodies
Cell bodiesMedium-sized neurons (15-25 μm diameter)
Dendritic fieldExtensive dendritic arborization within the Arc
Axonal projectionsWide-ranging projections to hypothalamic and extrahypothalamic targets
NPY36-amino acid neuropeptide, one of the most abundant peptides in the brain
AgRP132-amino acid melanocortin receptor antagonist
GABACo-transmitted as inhibitory neurotransmitter
KG Connections2 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (7)

Bacterial Enzyme-Mediated Dopamine Precursor Synthesis
Score: 0.36
APOE-Dependent Autophagy Restoration
Score: 0.63
Synthetic Biology BBB Endothelial Cell Reprogramming
Score: 0.57
Senescent Cell Mitochondrial DNA Release
Score: 0.54
Astrocytic Lactate Shuttle Enhancement for Grid Cell Bioener
Score: 0.41

Related Analyses (13)

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Knowledge Graph (2 edges)

ent-gene-8cd44c77 data_in benchmark_ot_ad_answer_key:NPY
benchmark_ot_ad_answer_key:NPY data_in ent-gene-8cd44c77