cell 2,977 words KG: ent-gene-8cd44c77 2026-03-24
kind:cell-typesection:cell-typesstate:published
Contents

Neuropeptide Y (NPY) Neurons

🔬 Protein Info
Gene SymbolNPY
Chromosome7p15.1
FunctionThe NPY gene encodes a prepropeptide that undergoes proteolytic processing to yield the mature NPY peptide.
Primary Expressionhippocampus, Hypothalamus, Brainstem, Thalamus, Amygdala
Amino Acids36 aa
PathwaysEr Stress, Mtor, Lipid Metabolism, Autophagy, Akt
Ensembl IDENSG00000157240
GeneCardsNPY
Human Protein AtlasNPY
ReceptorDistribution
Y1RCortex, hippocampus
Y2RHippocampus, amygdala
Y4RHypothalamus
Y5RHypothalamus
Y6RLimited species expression
Associated DiseasesALS, Alzheimer, Alzheimer'S Disease, Asthma
InteractionsMTOR, NPY1R, GAIN, CRH, NGF, BDNF
KG Connections315 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (6)

Synthetic Biology BBB Endothelial Cell Reprogramming
Score: 0.57
Senescent Cell Mitochondrial DNA Release
Score: 0.54
TREM2-DAP12 Signalosome Enhancement — Boosting PI3K-AKT-mTOR
Score: 0.45
Astrocytic Lactate Shuttle Enhancement for Grid Cell Bioener
Score: 0.41
Grid Cell-Specific Metabolic Reprogramming via IDH2 Enhancem
Score: 0.38

Related Analyses (10)

Selective vulnerability of entorhinal cortex layer II neuron
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
Mitochondrial transfer between neurons and glia
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived

Related Experiments (13)

Animal Model Comparison for Neurodegenerative Disease Therap
clinical · proposed · Score: 0.40
Endocannabinoid System Dysfunction Validation in Parkinson's
clinical · proposed · Score: 0.40
Glymphatic-Circadian Axis Enhancement Therapy for Parkinson'
clinical · proposed · Score: 0.40
Gut Microbiome-Derived Metabolites in Alpha-Synuclein Propag
clinical · proposed · Score: 0.40
Neural Oscillation Dysfunction Validation in Parkinson's Dis
clinical · proposed · Score: 0.40

Knowledge Graph (2 edges)

ent-gene-8cd44c77 data_in benchmark_ot_ad_answer_key:NPY
benchmark_ot_ad_answer_key:NPY data_in ent-gene-8cd44c77