cell 1,807 words KG: ent-gene-62458d07 2026-03-27
kind:cell-typesection:cell-typesstate:published
Contents

Vesicular Monoamine Transporter 2 (VMAT2) Neurons

🔬 Protein Info
Gene SymbolVMAT2
Full NameVesicular Monoamine Transporter 2
Chromosome10q25.2
Protein TypeCell Type
FunctionVMAT2 mediates vesicular uptake of monoamines
Primary Expressionall monoaminergic neurons (dopaminergic, serotonergic, noradrenergic)
Molecular Weight56 kDa
Amino Acids525 aa
Exons18
PathwaysAutophagy, Mapk, Mtor
NCBI Gene ID6844
Ensembl IDENSG00000165646
OMIM193001
GeneCardsVMAT2
Human Protein AtlasVMAT2
Associated DiseasesParkinson's disease
Known Drugs/Compoundslevodopa
InteractionsMTOR, NEURON, NEUROINFLAMMATION, NURR1, AUTOPHAGY, PARKINSON'S DISEASE
KG Connections27 knowledge graph edges
DatabasesGeneCardsUniProtHPASTRING

Knowledge Graph

Related Hypotheses (6)

Synthetic Biology BBB Endothelial Cell Reprogramming
Score: 0.57
Senescent Cell Mitochondrial DNA Release
Score: 0.54
Astrocytic Lactate Shuttle Enhancement for Grid Cell Bioener
Score: 0.41
Grid Cell-Specific Metabolic Reprogramming via IDH2 Enhancem
Score: 0.38
Age-Dependent Complement C4b Upregulation Drives Synaptic Vu
Score: 0.47

Related Analyses (11)

Selective vulnerability of entorhinal cortex layer II neuron
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
Metabolic reprogramming in neurodegenerative disease
neurodegeneration · completed
Mitochondrial transfer between neurons and glia
neurodegeneration · archived

Related Experiments (2)

ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40
Macroautophagy Dysfunction in PD - Experiment Design
clinical · proposed · Score: 0.40

Knowledge Graph (2 edges)

ent-gene-62458d07 data_in benchmark_ot_ad_answer_key:VMAT2
benchmark_ot_ad_answer_key:VMAT2 data_in ent-gene-62458d07