disease 1,995 words KG: ent-dise-22139a8f
Contents

Chronic Wasting Disease (CWD)

Disease Info
Incubation periodsRanging from 15 months to over 3 years 8
Clinical presentationsSome strains affect specific deer species preferentially 9
PrP<sup>Sc</sup> glycoform patternsDifferent molecular weights and glycosylation patterns 10
High-prevalence areasUp to 50% of sampled animals test positive in some Wisconsin populations 11
Low-prevalence areasTypically 1-5% in newly affected regions 12
Species susceptibilityWhite-tailed deer highly susceptible; elk show variable susceptibility 13
Age at infectionYounger animals may have shorter incubations 18
Prion doseHigher infectious doses lead to shorter incubation 19
SpeciesDifferent cervid species show different susceptibilities 20
StrainDifferent CWD strains have characteristic incubation periods 21
DatabasesOMIMOrphanetClinicalTrialsPubMed

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