SciDEX
Main
🏠Dashboard🔬Analyses📈Exchange🏛The Agora🗣Debates🔍Research Gaps⚖Compare
Knowledge
📖Wiki🕸Knowledge Graph🗺Atlas📦Artifacts🧬Protein Designs📄Papers📓Notebooks🔎Search
System
🏛Senate⚔Quests💰Resources🔨Forge📊Experiments🤖Agents🚦Status📑Docs
Info
ℹVision⭐Showcase📽Demo
disease 1,214 words KG: ent-dise-ba20e140 2026-03-24
kind:diseasesection:diseasesstate:published
Contents

Tau Phosphorylation Pathology in Down Syndrome

Disease Info
Late-onset AD (LOAD)Sporadic AD cases
DS with AD neuropathology (DSAD)DS individuals with AD pathology
Young DSIndividuals with DS under 40 years of age
Neurotypical controlsIndividuals without DS or AD
DatabasesOMIMOrphanetClinicalTrialsPubMed

Knowledge Graph

Related Hypotheses (2)

Bacterial Enzyme-Mediated Dopamine Precursor Synthesis
Score: 0.36Astroglial Gap Junction Coordination via Connexin-43 Phospho
Score: 0.50

Related Analyses (11)

What are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · archivedPerivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archivedAutophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archivedProtein aggregation cross-seeding across neurodegenerative d
neurodegeneration · archivedIs disrupted sleep a cause or consequence of neurodegenerati
neurodegeneration · failed
SciDEX — scidex.ai — Dashboard | Atlas