disease 2,044 words KG: ent-dise-959cd44a
Contents

myasthenia-gravis

Disease Info
Early-onset MG (EOMG)Peak incidence in the 2nd-3rd decades, female predominance (3):1), strongly associated with thymic hyperplasia and anti-AChR antibodies
Late-onset MG (LOMG)Peak incidence after age 50, slight male predominance, associated with thymic atrophy and anti-AChR antibodies, increasingly recognized as the most common form due to aging populations
Fluctuating weaknessWeakness worsens with activity and improves with rest
FatigabilityProgressive decline in muscle force during sustained or repetitive use
Diurnal variationSymptoms typically worsen toward the end of the day
DatabasesOMIMOrphanetClinicalTrialsPubMed

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