| Adrenal pheochromocytoma | Originates in the adrenal medulla, accounts for 80-85% of cases |
| Extra-adrenal paraganglioma | Arises from sympathetic ganglia, more likely to be malignant |
| Benign vs malignant | Approximately 10-15% are malignant with metastatic potential |
| Cardiovascular complications | Hypertensive cardiomyopathy, arrhythmias, myocardial infarction |
| Metabolic disturbances | Hyperglycemia, insulin resistance, weight loss |
| Neurological symptoms | Headaches, anxiety, panic attacks, tremor |
| Databases | OMIMOrphanetClinicalTrialsPubMed |