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disease 3,723 words KG: ent-dise-d5f19751 2026-03-29
kind:diseasesection:diseasesstate:published
Contents

Variably Protease-Sensitive Prionopathy (VPSPr)

Disease Info
129MMMajority of VPSPr cases
129VVMinority of VPSPr cases
129MVRare in VPSPr (contrast with sCJD)
Gene locationChromosome 20p13
DatabasesOMIMOrphanetClinicalTrialsPubMed

Knowledge Graph

Related Hypotheses (2)

Bacterial Enzyme-Mediated Dopamine Precursor Synthesis
Score: 0.36Pharmacological Enhancement of APOE4 Glycosylation
Score: 0.37

Related Analyses (4)

What are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · archivedAutophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archivedProtein aggregation cross-seeding across neurodegenerative d
neurodegeneration · archivedMetabolic reprogramming in neurodegenerative disease
neurodegeneration · completed

Related Experiments (7)

4R-Tau Targeting Therapies for PSP and CBS
clinical · proposed · Score: 0.40Anti-Tau Therapy Failure Mechanism in PSP — Why Clinical Tri
clinical · proposed · Score: 0.40Brainstem Circuit Modulation for PSP
clinical · proposed · Score: 0.40Levodopa Response Determinants in PSP — Biomarker-Guided Pre
clinical · proposed · Score: 0.40PSP and CBS Biomarker Validation Study
clinical · proposed · Score: 0.40
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