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disease 1,513 words KG: ent-dise-0db9a326
Contents

Dystonia

Disease Info
DopamineAltered dopaminergic signaling, particularly in DYT1 and DYT5 dystonia
GABAReduced inhibitory GABAergic transmission in the basal ganglia
SerotoninAltered serotonin metabolism in some forms
Endogenous cannabinoidsEndocannabinoid system involvement in movement control
DatabasesOMIMOrphanetClinicalTrialsPubMed

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Knowledge Graph

Related Hypotheses (6)

Cell-Type Specific TREM2 Upregulation in DAM Microglia
Score: 0.76GFAP-Positive Reactive Astrocyte Subtype Delineation
Score: 0.75The Mitochondrial-Lysosomal Metabolic Coupling Dysfunction
Score: 0.65Brain Insulin Resistance with Glucose Transporter Dysfunctio
Score: 0.60TREM2-mediated microglial tau clearance enhancement
Score: 0.59

Related Analyses (3)

SEA-AD Gene Expression Profiling — Allen Brain Cell Atlas
neurodegeneration · completedTau propagation mechanisms and therapeutic interception poin
neurodegeneration · archivedMetabolic reprogramming in neurodegenerative disease
neurodegeneration · completed

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