| Gene Symbol | GRM1 |
| Full Name | Glutamate Metabotropic Receptor 1 |
| Chromosome | 11q14.2 |
| Protein Type | Receptor |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Primary Expression | cerebellar Purkinje cells where it is essential for motor learning, and is also expressed in other brain regions including the hippocampus, basal gang |
| Molecular Weight | 150 kDa |
| Pathways | MAPK signaling, cascade:
### Signal Transduction Pathway |
| UniProt ID | Q9ULM0 |
| NCBI Gene ID | 2917 |
| Ensembl ID | ENSG00000168385 |
| OMIM | 604473 |
| GeneCards | GRM1 |
| Human Protein Atlas | GRM1 |
| Orthosteric binding site | High-affinity glutamate binding (Kd ~10 ΞM) |
| Associated Diseases | neurodegeneration |
| Interactions | MTOR |
| KG Connections | 8 knowledge graph edges |
| Databases | GeneCardsHPASTRING |