| Gene Symbol | Gem Nuclear Organelle Associated Protein 2 |
| Aliases | GEMIN2 gene in ALS and SMA |
| Chromosome | 14q13.2 |
| Function | is a critical component of the SMN (Survival of Motor Neuron) complex that is essential for spliceosomal small nuclear ribonucleoprotein (snRNP) biogenesis. |
| Gene Type | Protein coding |
| UniProt ID | O94876 |
| NCBI Gene ID | 25956 |
| Ensembl ID | ENSG00000145901 |
| OMIM | 609721 |
| SMN | The catalytic core, with an SMA domain and Tudor domain |
| GEMIN2 (SIP1) | RNA-binding adaptor that recruits snRNA |
| GEMIN1 | Scaffold protein organizing the complex |
| GEMIN3 (DDX20) | RNA helicase |
| GEMIN4 | Component with RNA-binding capacity |
| GEMIN5 | Component recognizing snRNA sequences |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsHPASTRING |
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