Contents

ATP6V0A1 Gene

🧬 Gene Info

Gene Symbol	ATP6V0A1
Chromosome	17q21.31 [@forgac2007]
Protein Type	Enzyme
Function	ATP6V0A1 encodes the largest subunit of the V0 sector (a-subunit isoform a1), which forms the proton channel across the lysosomal membrane [3].
Pathways	Role
UniProt ID	Q9Y282
NCBI Gene ID	271
Ensembl ID	ENSG00000115884
GeneCards	ATP6V0A1
Human Protein Atlas	ATP6V0A1
Pathway	Role
Autophagy-Lysosome Pathway	Proton gradient for lysosomal degradation
Synaptic Vesicle Cycle	Synaptic vesicle acidification
Mitochondrial Dynamics	Mitophagy regulation
ER Stress Response	UPR signaling
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

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