| Gene Symbol | C7 |
| Chromosome | 5p13.1 |
| Function | The primary function of C7 is in the terminal pathway of the complement system. |
| Amino Acids | 809 aa |
| Ensembl ID | ENSG00000124429 |
| GeneCards | C7 |
| Human Protein Atlas | C7 |
| Amyotrophic Lateral Sclerosis (ALS) | Complement activation is observed in ALS motor cortex and spinal cord |
| Frontotemporal Dementia | MAC deposition found in FTD brain tissue |
| Huntington's Disease | Complement proteins upregulated in HD brain |
| Liver | Primary site of complement protein synthesis |
| Brain | Expressed by astrocytes and microglia, particularly under inflammatory conditions |
| Kidney | Local synthesis in glomerular cells |
| Lung | Expression in alveolar epithelial cells |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |