| Gene Symbol | C8B |
| Chromosome | 2p13.2 |
| Function | The C8 beta chain functions as |
| Amino Acids | 579 aa |
| Ensembl ID | ENSG00000100031 |
| GeneCards | C8B |
| Human Protein Atlas | C8B |
| Complement Component 5 (C5) | Upstream component in MAC formation pathway |
| Complement Component 9 (C9) | Forms complete MAC with C8 |
| Complement Receptors | CR1, CR3, CR4 mediate downstream signaling |
| Microglia | Primary CNS cells expressing C8B in pathological states |
| Membrane Attack Complex (MAC) | Assembled structure containing C8B |
| Neuroinflammation | Primary pathological consequence of C8B activation |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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