Contents

CAPSN1

🧬 Gene Info

Gene Symbol	CAPSN1
Function	Calsyntenin-1 (also known as Alcadein-beta or CAPSN1) is a neuronal membrane protein belonging to the cadherin superfamily.
Primary Expression	neurons and is localized to synaptic membranes
Subcellular Localization	synaptic membranes
Molecular Weight	110 kDa
Amino Acids	3000 aa
UniProt ID	Q9BQP5
NCBI Gene ID	27245
Ensembl ID	ENSG00000171530
GeneCards	CAPSN1
Human Protein Atlas	CAPSN1
Amyotrophic Lateral Sclerosis (ALS)	Altered CAPSN1 expression has been reported in ALS motor neurons.
Schizophrenia	CAPSN1 genetic variants have been associated with schizophrenia risk.
N-terminal signal peptide	Targets protein to secretory pathway
Extracellular domain	Contains 10 cadherin repeats, ~3000 amino acids
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

Knowledge Graph