| Gene Symbol | CFI |
| Chromosome | 4p25.3 |
| Protein Type | Protease |
| Function | C3b Cleavage: Factor I cleaves C3b at specific sites, generating inactive C3b (iC3b) |
| Primary Expression | various tissues including the brain |
| Amino Acids | 406 aa |
| Ensembl ID | ENSG00000167644 |
| GeneCards | CFI |
| Human Protein Atlas | CFI |
| Glomerulonephritis | CFI mutations associated with renal disease |
| Infection Susceptibility | Particularly with encapsulated bacteria |
| Liver | Primary site of synthesis (hepatocytes) |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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