gene 4,939 words KG: CLCN10 2026-03-25
kind:genesection:genesstate:published
Contents

CLCN10 — Chloride Voltage-Gated Channel 10

🧬 Gene Info
Gene SymbolCLCN10
Full NameChloride Voltage-Gated Channel 10
Chromosome12p13.31
Protein FamilyCLC voltage-gated chloride channel family (CLCN1-7, CLCNKA, CLCNKB)
Functionis an integral membrane protein that functions primarily as a chloride channel or chloride-proton exchanger, depending on the specific isoform and cellular context.
Molecular Weight89 kDa
Amino Acids805 aa
Exons26
UniProt IDO75477 (CLCN10_HUMAN)
NCBI Gene ID11253
Ensembl IDENSG00000113337
OMIM600715
GeneCardsCLCN10
Human Protein AtlasCLCN10
Gene NameChloride Voltage-Gated Channel 10
Associated Diseasesneurodegeneration
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (5)

Mechanosensitive Ion Channel Reprogramming
Score: 0.51
Lysosomal Calcium Channel Modulation Therapy
Score: 0.49
Circadian-Gated Maresin Biosynthesis Amplification
Score: 0.47
Aquaporin-4 Polarization Enhancement via TREK-1 Channel Modu
Score: 0.44
Biorhythmic Interference via Controlled Sleep Oscillations
Score: 0.41

Related Analyses (5)

Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (12)

Animal Model Comparison for Neurodegenerative Disease Therap
clinical · proposed · Score: 0.40
Endocannabinoid System Dysfunction Validation in Parkinson's
clinical · proposed · Score: 0.40
Glymphatic-Circadian Axis Enhancement Therapy for Parkinson'
clinical · proposed · Score: 0.40
Gut Microbiome-Derived Metabolites in Alpha-Synuclein Propag
clinical · proposed · Score: 0.40
Neural Oscillation Dysfunction Validation in Parkinson's Dis
clinical · proposed · Score: 0.40

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in