gene 2,732 words KG: CLN7 2026-03-27
kind:genesection:genesstate:published
Contents

CLN7 — Ceroid Lipofuscinosis, Neuronal 7 (MFSD8)

🧬 Gene Info
Gene SymbolCLN7 / MFSD8
Full NameMajor Facilitator Superfamily Domain Containing 8
AliasesLINCL
Chromosome4q28.2
Protein TypeTransporter
Functionis a human gene that encodes a lysosomal membrane protein functioning as a putative transporter.
Primary ExpressionBrain, retina, liver, kidney, lung
Amino Acids476 aa
UniProt IDQ8N5M4
NCBI Gene ID256281
Ensembl IDENSG00000167695
OMIM614804
Protein ClassMFS transporter, lysosomal membrane protein
PhenotypeOnset Age
Classic LINCL2-7 years
Associated DiseasesPeripheral Neuropathy
KG Connections12 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (17)

Senescent Cell Mitochondrial DNA Release
Score: 0.54
Membrane Cholesterol Gradient Modulators
Score: 0.52
Near-infrared light therapy stimulates COX4-dependent mitoch
Score: 0.51
Ganglioside Rebalancing Therapy
Score: 0.50
APOE4-Selective Lipid Nanoemulsion Therapy
Score: 0.49

Related Analyses (3)

Circuit-level neural dynamics in neurodegeneration
neuroscience · archived
Metabolic reprogramming in neurodegenerative disease
neurodegeneration · completed
Cell type vulnerability in Alzheimers Disease (SEA-AD transc
neurodegeneration · archived

Related Experiments (13)

Animal Model Comparison for Neurodegenerative Disease Therap
clinical · proposed · Score: 0.40
Endocannabinoid System Dysfunction Validation in Parkinson's
clinical · proposed · Score: 0.40
ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40
Glymphatic-Circadian Axis Enhancement Therapy for Parkinson'
clinical · proposed · Score: 0.40
Gut Microbiome-Derived Metabolites in Alpha-Synuclein Propag
clinical · proposed · Score: 0.40

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in