gene 929 words KG: CLSTN1
Contents

Calsyntenin 1

🧬 Gene Info
Gene SymbolCLSTN1
Full NameCalsyntenin 1
Chromosome1p36.21
Protein TypeReceptor
FunctionIt interacts with the amyloid precursor protein (APP) and may regulate amyloid-beta production.
Primary Expressiondeveloping and mature neurons
UniProt IDQ9BZZ5
NCBI Gene ID64085
Ensembl IDENSG00000171603
OMIM611295
GeneCardsCLSTN1
Human Protein AtlasCLSTN1
CLSTN1High expression in cortex, hippocampus, and cerebellum. Enriched in postsynaptic densities. 6
LGI1Broad expression in brain, particularly hippocampus and cerebral cortex. Expressed in neurons and glia. 7
NRCAMExpressed in developing nervous system, particularly in axon tracts. In adults, expression persists in specific brain regions. 8
Associated Diseasesneurodegeneration
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Analyses (1)

Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (22)

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Metabolic Pathway-Targeted Therapy in ALS
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ALS Progression Rate Heterogeneity — mechanism and biomarker
clinical · proposed · Score: 0.40
ALS Regional Onset and Spread: Network-Level Staging Model
clinical · proposed · Score: 0.40
Sporadic ALS Initiation Biology: Deep Phenotyping of At-Risk
clinical · proposed · Score: 0.40

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in

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