Contents

CREB3L1 Gene

🧬 Gene Info

Gene Symbol	CREB3L1
Full Name	cAMP Responsive Element Binding Protein 3-Like 1
Chromosome	11p11.2
Protein Type	Transcription Factor
Function	CREB3L1 (OASIS) is a transcription factor with multiple roles
UniProt ID	Q7Z594
NCBI Gene ID	90993
Ensembl ID	ENSG00000127616
OMIM	612799
GeneCards	CREB3L1
Human Protein Atlas	CREB3L1
ER stress response	Activates UPR target genes under ER stress
Osteoblast differentiation	Essential for bone formation
Neuroprotection	Protects neurons from ER stress-induced cell death
Astrocyte function	Regulates astrocyte responses to injury
Associated Diseases	Hypochondroplasia (controversial), Cancers (multiple types), ER Stress-related disorders
Databases	GeneCards HPA STRING

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