gene 873 words KG: DHH 2026-03-27
kind:genesection:genesstate:published
Contents

DHH — Desert Hedgehog

🧬 Gene Info
Gene SymbolDHH
Full NameDesert Hedgehog
Chromosome12q13.12
Functionis a member of the Hedgehog signaling family with specialized roles in male gonad development, peripheral nerve myelination, and steroidogenesis.
Molecular Weight19 kDa
Amino Acids396 aa
Exons3
Ensembl IDENSG00000104970
GeneCardsDHH
Human Protein AtlasDHH
Receptor bindingDHH binds PTCH1 (Patched-1) receptor
SMO activationRelief of SMO (Smoothened) inhibition
GLI activationGLI transcription factors activated
Target genesGLI1, GLI2, PTCH1, HHIP, BMP
Leydig cell differentiationDHH from Sertoli cells induces Leydig cell development
Associated Diseasesneurodegeneration
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph