gene 741 words KG: DNAJC18
Contents

DNAJC18 Gene

🧬 Gene Info
Gene SymbolDnaJ Heat Shock Protein Family Member C18
AliasesDNAJC18
Chromosome4q22.1
Protein TypeChaperone
Functionis a member of the DnaJ/Hsp40 family of molecular chaperones.
Subcellular Localizationmitochondria and assist in protein import and quality control. Further research is needed to determine if DNAJC18 has si
Amino Acids70 aa
Gene TypeProtein coding
UniProt IDQ9H7E4
NCBI Gene ID54962
OMIM610091
Protein Folding AssistanceLike other DnaJ proteins, DNAJC18 works in conjunction with Hsp70 family chaperones to facilitate proper protein folding
Protein Quality ControlHelps recognize and target misfolded proteins for degradation via the proteasome
Stress ResponseUpregulated under cellular stress conditions including heat shock and oxidative stress
Transmembrane Protein ProcessingSome DnaJ proteins specialize in processing polytopic membrane proteins, a function that may extend to DNAJC18
Associated Diseasesneurodegeneration
DatabasesGeneCardsHPASTRING

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