| Gene Symbol | DUOX1 |
| Full Name | Dual Oxidase 1 |
| Chromosome | 15q21.1 |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Primary Expression | various tissues including the thyroid, lung, and gastrointestinal tract, where it plays critical roles in hydrogen peroxide production, host defense |
| Molecular Weight | 175 kDa |
| Amino Acids | 545 aa |
| UniProt ID | [Q9UHD8](https://www.uniprot.org/uniprot/Q9UHD8) |
| Ensembl ID | ENSG00000155505 |
| OMIM | 607709 |
| GeneCards | DUOX1 |
| Human Protein Atlas | DUOX1 |
| Peroxidase activity | Unlike other NOX enzymes, DUOX has intrinsic peroxidase activity |
| Calcium dependence | Directly activated by calcium binding to EF-hand domains |
| Maturation factor requirement | Requires DUOXA1 for proper folding, trafficking, and function |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsNCBI GeneHPASTRING |