| Gene Symbol | ELOVL5 |
| Full Name | Elongation of Very Long Chain Fatty Acids 5 |
| Aliases | Page for ELOVL5 |
| Protein Type | Enzyme |
| Function | ELOVL5 (Elongation of Very Long Chain Fatty Acids 5) is an endoplasmic reticulum membrane-bound enzyme that catalyzes the rate-limiting step in the elongation of polyunsaturated fatty acids (PUFAs). |
| Primary Expression | multiple tissues with brain-relevant localization:
- Brain: Cerebellum (Purkinje cells), hippocampus, [cortex](/brai |
| UniProt ID | [Q9NYP7](https://www.uniprot.org/uniprot/Q9NYP7) |
| Ensembl ID | ENSG00000012660 |
| GeneCards | ELOVL5 |
| Human Protein Atlas | ELOVL5 |
| Brain | Cerebellum (Purkinje cells), hippocampus, cortex |
| Retina | Photoreceptor cells and retinal pigment epithelium |
| Liver | Major site of fatty acid elongation |
| Testis | High expression for sperm membrane synthesis |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsNCBI GeneHPASTRING |