| Gene Symbol | ERCC8 |
| Aliases | CSA |
| Function | encodes a key DNA repair protein essential for transcription-coupled nucleotide excision repair (TC-NER). |
| Primary Expression | the central nervous system: |
| Amino Acids | 396 aa |
| Ensembl ID | ENSG00000166167 |
| GeneCards | ERCC8 |
| Human Protein Atlas | ERCC8 |
| ERCC8 (CSA) | The 396-amino acid scaffold protein |
| ERCC6 (CSB) | ATP-dependent chromatin remodeler |
| DET1 | E3 ubiquitin ligase component |
| CUL4A | E3 ubiquitin ligase core |
| RBX1 | RING-box protein |
| DDB1 | DNA damage binding protein |
| WD40 repeats | Form a β-propeller structure for protein-protein interactions |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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