gene 1,064 words KG: GFRA3
Contents

GFRA3 Gene

🧬 Gene Info
Gene SymbolGFRA3
Chromosome5q31.1
Protein TypeReceptor
Functionis a GPI-anchored cell surface receptor that serves as the primary receptor for artemin (ARTN), a member of the glial cell line-derived neurotrophic factor (GDNF) family.
Primary Expressionperipheral nervous system tissues, with lower expression in some brain regions
Molecular Weight~52 kDa (precursor), ~35 kDa (mature)
Amino Acids465 aa
PathwaysPI3K, MAPK
UniProt IDQ9Y5R5
NCBI Gene ID63954
OMIM605331
GeneCardsGFRA3
Human Protein AtlasGFRA3
Protein Length465 amino acids
Protein ClassGDNF family receptor
Associated Diseasesneurodegeneration
DatabasesGeneCardsHPASTRING

Knowledge Graph