| Gene Symbol | GPX8 |
| Full Name | Glutathione Peroxidase 8 |
| Chromosome | 5q31.2 |
| Function | GPX8 exhibits several key functions |
| Primary Expression | Liver, Kidney, Brain, Intestine |
| UniProt ID | Q9D0M5 |
| NCBI Gene ID | 493869 |
| Ensembl ID | ENSG00000164106 |
| GeneCards | GPX8 |
| Human Protein Atlas | GPX8 |
| ER Oxidative Stress Defense | Reduces peroxides in the ER lumen, protecting against oxidative protein damage[@ramming2020] |
| UPR Regulation | Plays a role in modulating the PERK and IRE1α branches of the unfolded protein response[@chen2019] |
| Protein Folding | Maintains ER redox balance necessary for proper disulfide bond formation |
| Calcium Homeostasis | Helps regulate ER calcium storage through oxidative stress mitigation[@li2018] |
| Databases | GeneCardsHPASTRING |
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