gene 2,107 words KG: GTF2H5
Contents

GTF2H5 — General Transcription Factor IIH Subunit 5 (TTDA)

🧬 Gene Info
Gene SymbolGTF2H5
Full NameGeneral Transcription Factor IIH Subunit 5 (TTDA)
Chromosome6q25.3
Protein TypeTranscription Factor
Functionencodes a small 71-amino acid subunit of the Transcription Factor IIH (TFIIH) complex that is essential for both transcription initiation and nucleotide excision repair (NER) [@gigliamari2004].
Molecular Weight8 kDa
Amino Acids71 aa
UniProt ID[Q86WW5](https://www.uniprot.org/uniprot/Q86WW5)
Ensembl IDENSG00000167291
OMIM607332
GeneCardsGTF2H5
Human Protein AtlasGTF2H5
N-terminal domainInvolved in protein-protein interactions
Dimerization interfaceForms the functional homodimer
TFIIH interaction surfaceBinds specifically to the TFIIH core complex
Associated Diseasesneurodegeneration
DatabasesGeneCardsNCBI GeneHPASTRING

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