gene 1,559 words KG: GUCY1A1 2026-03-26
kind:genesection:genesstate:published
Contents

GUCY1A1 Gene

🧬 Gene Info
Gene SymbolGUCY1A1
Full NameGuanylate Cyclase 1 Soluble Subunit Alpha 1
AliasesGUCY1A1, sGC-α1, GUCY1A, α1-sGC
Chromosome4q31.3
Protein FamilySoluble guanylate cyclase subunits (GUCY1A1, GUCY1B1)
FunctionSoluble guanylate cyclase is activated by
Primary Expressionthe brain and vascular endothelium, making it a critical nexus for NO-mediated signaling in both physiological and pathological states
Amino Acids619 aa
UniProt IDQ02108
NCBI Gene ID2982
Ensembl IDENSG00000147854
OMIM139396
GeneCardsGUCY1A1
Human Protein AtlasGUCY1A1
Protein ClassEnzyme - Guanylate cyclase
Associated Diseasesneurodegeneration
DatabasesGeneCardsHPASTRING

Knowledge Graph