gene 907 words KG: HOXA1 2026-03-24
kind:genesection:genesstate:published
Contents

HOXA1 Gene

🧬 Gene Info
Gene SymbolHOXA1
Chromosome7p15.2
Protein FamilyHomeobox family, HoxA cluster
Protein TypeTranscription Factor
Functionis an important component in the neurobiology of neurodegenerative diseases.
Primary Expressionneural stem cells of the subventricular zone - Neuronal Plasticity: May regulate experience-dependent gene expression - Circuit Maintenance: I
Subcellular LocalizationNucleus
Molecular Weight37.3 kDa
Amino Acids355 aa
PathwaysModulates Wnt, BMP, and FGF signaling
UniProt ID[P49639](https://www.uniprot.org/uniprot/P49639)
GeneCardsHOXA1
Human Protein AtlasHOXA1
HomeodomainA 60-amino acid DNA-binding helix-turn-helix motif
N-terminal transactivation domainRich in acidic residues
Associated Diseasesneurodegeneration
DatabasesGeneCardsNCBI GeneHPASTRING

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