gene 2,696 words KG: HSPBAP1
Contents

HSPBAP1 — HSPB Associated Protein 1

🧬 Gene Info
Gene SymbolHSPBAP1
Full NameHSPB Associated Protein 1
Chromosome4q21
Functionis a human gene located on chromosome 4q21 that encodes a protein implicated in the small heat shock protein (sHsp) family network.
Primary ExpressionCortex, Hippocampus, Cerebellum, Spinal cord
Molecular Weight50 kDa
Amino Acids466 aa
UniProt IDQ9N2I8
NCBI Gene ID79668
Ensembl IDENSG00000125821
OMIM610092
GeneCardsHSPBAP1
Human Protein AtlasHSPBAP1
Chaperone network amplificationBy binding to multiple sHsp family members, HSPBAP1 may extend the substrate scope of the chaperone network
Complex formationHSPBAP1 may serve as a scaffold for assembling multi-sHsp complexes with enhanced protective function
Associated Diseasesneurodegeneration
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (18)

APOE-Dependent Autophagy Restoration
Score: 0.84
Senescent Cell Mitochondrial DNA Release
Score: 0.74
Near-infrared light therapy stimulates COX4-dependent mitoch
Score: 0.74
Senescence-Associated Myelin Lipid Remodeling
Score: 0.73
Phase-Separated Organelle Targeting
Score: 0.73

Related Analyses (8)

Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in

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