| Gene Symbol | KCNA6 |
| Aliases | Potassium Voltage-Gated Channel Subfamily A Member 6 |
| Protein Type | Gene |
| Function | encodes a six-transmembrane (S1–S6) voltage-gated potassium channel alpha subunit with the canonical pore-loop selectivity filter between S5 and S6. |
| Molecular Weight | 60 kDa |
| GeneCards | KCNA6 |
| Human Protein Atlas | KCNA6 |
| Tetramerization competence | Kv1.6 can co-assemble with other Kv1 subunits, altering activation/inactivation kinetics versus homomeric channels.[@chandy1995][@jan2012] |
| Delayed-rectifier behavior | Supports action-potential repolarization and limits repetitive burst firing in excitable cells.[@chandy1995][@long2005] |
| Subcellular targeting logic | Kv-family channels are differentially targeted to soma, dendrites, axons, and presynaptic compartments through motif-dependent trafficking and scaffold interactions.[@chandy1995][@misonou2004] |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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