| Gene Symbol | KCNJ12 |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Primary Expression | Brain, heart, and skeletal muscle |
| GeneCards | KCNJ12 |
| Human Protein Atlas | KCNJ12 |
| Channel Family | Inwardly rectifying potassium (Kir) channels |
| Subunit | Kir2.2 (encoded by KCNJ12) |
| Tetrameric assembly | Forms functional channels as tetramers |
| Resting membrane potential | Maintains negative resting potential |
| Neuronal excitability | Controls input resistance and time constant |
| Potassium homeostasis | Regulates extracellular K+ levels |
| Cardiac function | Automaticity in the heart |
| Development | Neural tube closure |
| Developmental delay | Intellectual disability |
| Autism spectrum disorder | Social communication deficits |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |