| Gene Symbol | LFNG |
| Aliases | Page for LFNG Gene |
| Chromosome | 7q32 |
| Protein Type | Transferase |
| Function | Lunatic Fringe (LFNG) is a member of the Fringe family of glycosyltransferases that catalyze the addition of N-acetylglucosamine (GlcNAc) to O-fucose residues on Notch receptors. |
| Primary Expression | hippocampus (dentate gyrus), subventricular zone, and cerebellar Purkinje cells |
| Pathways | Notch, Notch signaling, NOTCH |
| Ensembl ID | ENSG00000166323 |
| GeneCards | LFNG |
| Human Protein Atlas | LFNG |
| Notch Receptors and Ligands | Primary substrates of LFNG glycosylation |
| POFUT1 | Upstream O-fucosyltransferase required for LFNG substrate recognition |
| RFNG and MFNG | Related fr |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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