| Gene Symbol | LIG3 |
| Full Name | DNA Ligase 3 |
| Chromosome | 17q12 |
| Protein Type | Enzyme |
| Function | DNA Ligase 3 is a key enzyme in DNA repair, participating in multiple DNA repair pathways. |
| Primary Expression | neurons and glia - High expression in regions with active DNA repair - Mitochondrial isoform important in high-energy demand neurons - Downregulated i |
| Subcellular Localization | s including nuclear and mitochondrial forms. Lig3 is particularly enriched in neural tissues, where its expression level |
| UniProt ID | P18858 |
| Ensembl ID | ENSG00000076544 |
| GeneCards | LIG3 |
| Human Protein Atlas | LIG3 |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsNCBI GeneHPASTRING |
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