gene 1,377 words KG: MFRP 2026-03-26
kind:genesection:genesstate:published
Contents

MFRP - Membrane Frizzled-Related Protein

🧬 Gene Info
Gene SymbolMFRP
Full NameMembrane-Type Frizzled-Related Protein
Chromosome11q14.1
Protein TypeReceptor
Functionis a member of the frizzled family of transmembrane receptors that play critical roles in the Wnt signaling pathway
Primary Expressionthe retina and plays essential roles in:
Amino Acids582 aa
UniProt ID[Q9BYD4](https://www.uniprot.org/uniprot/Q9BYD4)
Ensembl IDENSG00000133105
OMIM607502
GeneCardsMFRP
Human Protein AtlasMFRP
Wnt/β-catenin pathwayCan either enhance or inhibit canonical Wnt signaling depending on cellular context
Planar Cell Polarity (PCP) pathwayInvolved in non-canonical Wnt signaling affecting cytoskeletal organization
Frizzled receptor interactionsForms heterodimers with other frizzled family members to modulate their activity
Associated Diseasesneurodegeneration
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph