gene 2,227 words KG: NCF4
Contents

NCF4 (Neutrophil Cytosolic Factor 4)

🧬 Gene Info
Gene SymbolNCF4
Full NameNeutrophil Cytosolic Factor 4 (p40^phox^)
Protein TypeEnzyme
Functionis a regulatory subunit of the NADPH oxidase (NOX2) complex that plays a critical role in generating reactive oxygen species (ROS) in phagocytic cells.
Primary Expressionmicroglia—the resident immune cells of the brain—where it contributes to neuroinflammatory processes that are central to neurodegenerative disease pat
Amino Acids80 aa
UniProt IDQ9UHI5
NCBI Gene ID3074
Ensembl IDENSG00000100129
OMIM604467
GeneCardsNCF4
Human Protein AtlasNCF4
Chr Location22q13.1
Encoded Proteinp40^phox^
Associated Diseasesneurodegeneration
DatabasesGeneCardsHPASTRING

Knowledge Graph