gene 2,499 words KG: NDUFAF5 2026-03-26
kind:genesection:genesstate:published
Contents

NDUFAF5 Gene

🧬 Gene Info
Gene SymbolNDUFAF5
Full NameNADH Dehydrogenase Complex Assembly Factor 5
Chromosome20p12.1
Functionis a critical mitochondrial protein encoding a mitochondrial complex I assembly factor with a SAM (Sterile Alpha Motif) domain.
Primary Expressiontissues with high mitochondrial energy demands, including the brain, heart, skeletal muscle, and liver
Amino Acids405 aa
UniProt ID[Q9NYY8](https://www.uniprot.org/uniprot/Q9NYY8)
Ensembl IDENSG00000120738
OMIM612360
GeneCardsNDUFAF5
Human Protein AtlasNDUFAF5
Associated Diseasesneurodegeneration
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (21)

CYP46A1 Overexpression Gene Therapy
Score: 0.63
Digital Twin-Guided Metabolic Reprogramming
Score: 0.61
Chromatin Accessibility Restoration via BRD4 Modulation
Score: 0.56
Senescent Cell Mitochondrial DNA Release
Score: 0.54
Epigenetic Memory Erasure via TET2 Activation
Score: 0.52

Related Analyses (3)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in