gene 2,499 words KG: NDUFAF5
Contents

NDUFAF5 Gene

🧬 Gene Info
Gene SymbolNDUFAF5
Full NameNADH Dehydrogenase Complex Assembly Factor 5
Chromosome20p12.1
Functionis a critical mitochondrial protein encoding a mitochondrial complex I assembly factor with a SAM (Sterile Alpha Motif) domain.
Primary Expressiontissues with high mitochondrial energy demands, including the brain, heart, skeletal muscle, and liver
Amino Acids405 aa
UniProt ID[Q9NYY8](https://www.uniprot.org/uniprot/Q9NYY8)
Ensembl IDENSG00000120738
OMIM612360
GeneCardsNDUFAF5
Human Protein AtlasNDUFAF5
Associated Diseasesneurodegeneration
DatabasesGeneCardsNCBI GeneHPASTRING

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NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (21)

Chromatin Accessibility Restoration via BRD4 Modulation
Score: 0.77
CYP46A1 Overexpression Gene Therapy
Score: 0.77
Senescent Cell Mitochondrial DNA Release
Score: 0.74
Near-infrared light therapy stimulates COX4-dependent mitoch
Score: 0.74
Epigenetic Memory Erasure via TET2 Activation
Score: 0.74
TFAM overexpression creates mitochondrial donor-recipient gr
Score: 0.73
TET2-Mediated Demethylation Rejuvenation Therapy
Score: 0.71
Perforant Path Presynaptic Terminal Protection Strategy
Score: 0.70
Mitochondrial Transfer Pathway Enhancement
Score: 0.70
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
RAB27A-dependent extracellular vesicle engineering for mitoc
Score: 0.67
Partial Neuronal Reprogramming via Modified Yamanaka Cocktai
Score: 0.67
GAP43-mediated tunneling nanotube stabilization enhances neu
Score: 0.67
Temporal TET2-Mediated Hydroxymethylation Cycling
Score: 0.66
Mitochondrial RNA Granule Rescue Pathway
Score: 0.66
KDM6A-Mediated H3K27me3 Rejuvenation
Score: 0.65
DNMT1-Targeting Antisense Oligonucleotide Reset
Score: 0.65
Mitochondrial SPM Synthesis Platform Engineering
Score: 0.65
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.62
CX43 hemichannel engineering enables size-selective mitochon
Score: 0.57
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Related Analyses (3)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in

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