| Gene Symbol | PLXNA1 |
| Chromosome | 3q21.3 |
| Protein Type | Gene |
| Function | encodes a transmembrane receptor for semaphorins, playing critical roles in axonal guidance, neural circuit formation, and synaptic plasticity throughout development and in the adult nervous system. |
| Molecular Weight | 210 kDa |
| Amino Acids | 018 aa |
| Exons | 31 |
| Pathways | PI3K, MAPK |
| GeneCards | PLXNA1 |
| Human Protein Atlas | PLXNA1 |
| Cerebellum | Purkinje cells |
| Spinal cord | Motor neurons (alpha and gamma motor neurons) |
| Dorsal root ganglia | Sensory neurons |
| Developing brain | Particularly during embryogenesis and early postnatal periods |
| Plexin homology (PH) domain | Contains GTPase-activating protein (GAP) activity[@plexin2018] |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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