gene 753 words KG: PNMT
Contents

PNMT Gene

🧬 Gene Info
Gene SymbolPNMT
Chromosome17q21.2
Protein TypeGene
FunctionPNMT catalyzes the methylation of norepinephrine to produce epinephrine
Primary Expressionthe adrenal medulla and in certain brain regions, particularly the locus coeruleus
Molecular Weight30 kDa
Amino Acids291 aa
GeneCardsPNMT
Human Protein AtlasPNMT
GenePNMT (chromosome 17q21.2)
Protein ClassMethyltransferase (EC 2.1.1.28)
Protein Size291 amino acids
Primary LocalizationCytoplasm of adrenal medulla chromaffin cells, locus coeruleus neurons
Cofactor RequirementS-adenosylmethionine (SAM)
Disease AssociationsStress disorders, cardiovascular disease, neurodegenerative conditions
Associated DiseasesStress disorders, cardiovascular disease, neurodegenerative conditions
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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