gene 1,046 words KG: POLM 2026-03-27
kind:genesection:genesstate:published
Contents

POLM Gene

🧬 Gene Info
Gene SymbolPOLM
Full NameDNA Polymerase Mu
Chromosome7p13
FunctionDNA polymerase mu (Pol μ) is a specialized DNA polymerase that performs several critical functions in DNA repair and immune system development
Molecular Weight55 kDa
Amino Acids494 aa
UniProt IDQ9NP87
NCBI Gene ID11298
Ensembl IDENSG00000157212
OMIM605515
GeneCardsPOLM
Human Protein AtlasPOLM
DiseaseMechanism
Alzheimer's DiseaseImpaired NHEJ repair leads to accumulation of DNA double-strand breaks in neurons
Parkinson's DiseaseDefective DNA repair contributes to dopaminergic neuron loss
Associated Diseasesneurodegeneration
DatabasesGeneCardsHPASTRING

Knowledge Graph