| Gene Symbol | PRDX4 |
| Full Name | Peroxiredoxin 4 |
| Chromosome | 19p13.13 |
| Protein Type | Enzyme |
| Function | PRDX4 functions as a thiol-dependent peroxidase using a conserved cysteine residue (Cys^157) at its active site to reduce peroxides[@park2000]. |
| Primary Expression | Cerebral cortex, Hippocampus, Liver, Kidney |
| Subcellular Localization | positions PRDX4 as a critical regulator of ER redox homeostasis and extracellular oxidative stress |
| Pathways | NF-κB |
| UniProt ID | Q9BZL1 |
| NCBI Gene ID | 10599 |
| Ensembl ID | ENSG00000179673 |
| OMIM | 607723 |
| GeneCards | PRDX4 |
| Human Protein Atlas | PRDX4 |
| ER Redox Homeostasis | Maintains the ER lumen in a reduced state necessary for proper protein folding |
| Databases | GeneCardsHPASTRING |
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