gene 2,337 words KG: RAB22A 2026-03-27
kind:genesection:genesstate:published
Contents

RAB22A

🧬 Gene Info
Gene SymbolRAB22A
Full NameMember RAS Oncogene Family
Chromosome20q13.32
Functionis a small GTPase belonging to the RAB GTPase family that plays critical roles in endocytic trafficking and early endosome organization.
Molecular Weight24 kDa
Amino Acids213 aa
UniProt IDQ9H832
NCBI Gene ID57403
Ensembl IDENSG00000027869
OMIM605241
GeneCardsRAB22A
Human Protein AtlasRAB22A
G1 motif (P-loop)Nucleotide binding site
G2 motifSwitch region I, undergoes conformational change upon GTP binding
G3 motifSwitch region II, critical for effector interactions
Associated Diseasesneurodegeneration
DatabasesGeneCardsHPASTRING

Knowledge Graph