gene 1,828 words KG: RAPGEF1
Contents

RAPGEF1 — Rap Guanine Nucleotide Exchange Factor 1 (C3G)

🧬 Gene Info
Gene SymbolRAPGEF1
Full NameRap Guanine Nucleotide Exchange Factor 1
Chromosome9q34.13
Functionis a critical signaling molecule that serves as a guanine nucleotide exchange factor (GEF) for small GTPases Rap1 and R-Ras.
Primary Expressionthe central nervous system, particularly in hippocampal neurons, cortical pyramidal cells, and cerebellar Purkinje cells
Molecular Weight~116 kDa
Amino Acids047 aa
Exons23
UniProt IDQ9Y238
NCBI Gene ID2889
Ensembl IDENSG00000107281
OMIM600996
GeneCardsRAPGEF1
Human Protein AtlasRAPGEF1
Alternative NamesC3G, GRF2, CRK SH3-binding guanine nucleotide exchange factor
Associated Diseasesneurodegeneration
DatabasesGeneCardsHPASTRING

Knowledge Graph