gene 3,060 words KG: RGS16
Contents

RGS16 Gene

🧬 Gene Info
Gene SymbolRGS16
Full NameRegulator of G Protein Signaling 16
Chromosome19q13.12
Functionencodes a member of the RGS family of GTPase-activating proteins that negatively regulate G protein-coupled receptor signaling [1][2].
Primary Expressionthe suprachiasmatic nucleus, the master circadian clock of the hypothalamus [6]
Amino Acids120 aa
UniProt IDO15410
NCBI Gene ID6004
Ensembl IDENSG00000128283
OMIM602811
GeneCardsRGS16
Human Protein AtlasRGS16
RGS DomainThe conserved catalytic domain that mediates GAP activity toward Gα subunits
N-terminal RegionContains a cysteine-rich sequence that may mediate palmitoylation and membrane association
PDZ-Binding MotifC-terminal sequence that allows interaction with PDZ domain-containing proteins
Associated Diseasesneurodegeneration
DatabasesGeneCardsHPASTRING

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