| Gene Symbol | RIMS2 |
| Protein Type | Gene |
| Function | RIMS2 (Regulating Synaptic Membrane Exocytosis 2), also known as RIM2, is a critical presynaptic protein that regulates synaptic vesicle docking, priming, and fusion. |
| Amino Acids | 777 aa |
| UniProt ID | Q9UQ26 |
| Ensembl ID | ENSG00000155380 |
| GeneCards | RIMS2 |
| Human Protein Atlas | RIMS2 |
| Synaptic vesicle priming | RIMS2 helps vesicles reach a fusion-ready state |
| Calcium channel coupling | RIMS2 links voltage-gated calcium channels to vesicle release sites |
| Active zone organization | RIMS2 is a core component of the active zone cytomatrix |
| Synaptic vesicle recycling | Regulates endocytosis and vesicle replenishment |
| RAB3A/B | Small GTPases that regulate vesicle trafficking |
| MUNC13 | Vesicle priming proteins |
| CAPS | Vesicle priming factors |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsNCBI GeneHPASTRING |
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