| Gene Symbol | SHRM3 |
| Full Name | Shroom Family Member 3 |
| Chromosome | 19q13.42 |
| Function | is an actin-binding protein that plays critical roles in cellular morphogenesis and tissue development [simic2018](https://pubmed. |
| Primary Expression | both developing and adult tissues, with particularly high expression in the nervous system and kidney [hatano2020](https://pubmed |
| Subcellular Localization | 2. **Central region**: Contains binding sites for actin and myosin |
| Molecular Weight | 210 kDa |
| Amino Acids | 1934 aa |
| Ensembl ID | ENSG00000104892 |
| GeneCards | SHRM3 |
| Human Protein Atlas | SHRM3 |
| Neural plate bending | Initiates folding of the neural plate |
| Neural fold elevation | Promotes elevation of neural folds |
| Fusion of folds | Facilitates closure at the midline |
| Spina bifida prevention | Proper SHRM3 function prevents neural tube defects |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |