gene 871 words KG: SLC22A6
Contents

SLC22A6 — Solute Carrier Family 22 Member 6 (OAT1)

🧬 Gene Info
Gene SymbolSLC22A6
Full NameSolute Carrier Family 22 Member 6 (OAT1)
Chromosome11q13
Protein TypeTransporter
Functionis a major urate transporter in the kidney.
Primary Expressionthe kidney proximal tubules
Subcellular Localizationthe basolateral membrane of tubular cells, where it interfaces with peritubular capillaries. Minor expression has been d
UniProt IDO15259
NCBI Gene ID6579
Ensembl IDENSG00000197905
OMIM607482
GeneCardsSLC22A6
Human Protein AtlasSLC22A6
Endogenous metabolitesUrate, prostaglandins, hippurates, indoxyl sulfate, kynurenic acid
Environmental toxinsPara-aminohippurate (PAH), ochratoxin A
Associated Diseasesneurodegeneration
DatabasesGeneCardsHPASTRING

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